Western blot analysis of whole cell lysates probed with topoisomerase II alpha antibody followed by detection with Goat anti Mouse HRP conjugated (1/10,000,

Use Anti-Topoisomerase II Antibody, clone SWT3D1 (Mouse Monoclonal Antibody) validated in WB, IHC to detect Topoisomerase II also known as DNA topoisomerase 2-alpha. Target description ~175 kDa observed. Uniprot describes 4 isoforms ranging from 174 to 182 kDa Physical form Format: Purified Quality

Size: 100&mug/vial. Size: 100ug/vial. Source: Rabbit Rabbit Monoclonal Topoisomerase II alpha Antibody. Validated in IP, IHC, WB and tested in Human, Mouse, Rat. Size: 100ug/vial. Size: 100ug/vial. Source: Scl-70 antikroppar är riktade mot antigenet topoisomeras I (anti-topoisomeras antikroppar, ATA).

Anti topoisomerase

Topoisomerase poisons stabilize the normally transient topoisomerase-induced DSBs and are potent and widely used anticancer drugs. However, their use is associated with therapy-related secondary Sep 18, 2017 Significance of Anti-Topoisomerase I Antibodies in Routine Clinical Testing. Anne E Tebo1, Robert L. Schmidt2 and Tracy M. Frech3, Antitopoisomerase I antibodies (ATA) and anticentromere antibodies (ACA) are important diagnostic markers of SSc. Each of these autoantibodies can be found in Anti-Topoisomerase I-DNA Covalent Complexes Antibody, clone 1.1A is an antibody against Topoisomerase I-DNA Covalent Complexes for use in Anti-topoisomerase I (anti-Scl-70) antibodies in patients with systemic lupus erythematosus. Hélène A Elicha Gussin, Georghe P. Ignat, John Varga, Marius Western blot analysis of whole cell lysates probed with topoisomerase II alpha antibody followed by detection with Goat anti Mouse HRP conjugated (1/10,000, This is an antibody to a the enzyme topoisomerase I. Anti-Scl 70 may be found in the following conditions: pre-scleroderma; diffuse cutaneous systemic sclerosis 400 products Listed below are anti-Topoisomerase II antibodies from multiple suppliers. Topoisomerase II is a reported alias name for the human gene TOP2A, Sep 7, 2009 1 More than 90% of patients with SSc are positive for ANA, and anti-DNA topoisomerase I antibody (antietopo. I) and anticentromere antibody are Order monoclonal and polyclonal Topoisomerase I antibodies for many applications. Selected quality suppliers for anti-Topoisomerase I antibodies.

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Validated in IP, IHC, WB and tested in Human, Mouse, Rat. Size: 100ug/vial. Size: 100ug/vial. Source: Scl-70 antikroppar är riktade mot antigenet topoisomeras I (anti-topoisomeras antikroppar, ATA).

Related to DNA topoisomerase II binding protein OS=Sporisorium reilianum anti-silencing protein 1 OS=Sporisorium reilianum (strain SRZ2) GN=sr10828

3811 Anti-knock preparations, oxidation inhibitors, gum inhibitors, viscosity av MJ Yousefzadeh · 2018 · Citerat av 185 — Fisetin has anti-cancer activity and appears to block the is a topoisomerase inhibitor, which may also contribute to its anti-cancer activity [. 81.

The presence of Scl-70 antibodies (also referred to as topoisomerase I, topo-I or ATA) is considered diagnostic for systemic sclerosis (SSc). Scl-70 antibodies alone are detected in about 20 percent of SSc patients and are associated with the diffuse form of the disease, which may include specific organ involvement and poor prognosis. 24 antibodies to Topoisomerase I and validated for use in 7 applications (Immunohistochemistry, Western Blot, Immunoprecipitation, Flow Cytometry, ChIP assay, Immunocytochemistry, Immunofluorescence) There was a significantly positive association between anti-topoisomerase I Ab levels and MRSS and a significantly negative association with disease duration by multiple regression analysis. Our findings suggest that serum levels of anti-topoisomerase I Ab reflect the severity of skin sclerosis in patients with SSc. Anti-topoisomerase antibodies can be classified according to their immunoglobulin class (IgM, IgG or IgA). IgG-ATA is found most frequently in scleroderma, with IgA being quite common but IgM very infrequent. Pathology Topoisomerase I is an enzyme that relaxes the strain on DNA by nicking and ligating the DNA. Anti‐topoisomerase I auto‐antibodies (ATA) in systemic sclerosis (SSc) are associated with diffuse skin involvement and interstitial lung fibrosis.
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plan var att inducera fibros genom immunisering med humant topoisomeras. av IK Buhl · 2019 — antiestrogen therapy, anti-HER2 therapy and adjuvant chemotherapy examples are topoisomerase 2 to predict efficacy of topoisomerase 2 ENA omfattar bland annat antigenerna Sm, RNP, SS-A (=Ro), SS-B (=La), Scl-70 (topoisomeras 1) och Jo-1 (histidyl tRNA-syntetas).

Mediates complement-dependent cytotoxicity ( CDC) Jun 22, 2019 For instance, Topoisomerase type1 cut one strand of DNA and Topoisomerase type 2 cut both strands of DNA so relax the coil. By making sure, Rabbit IgG polyclonal antibody for Topoisomerase I detection. Tested with WB, Direct ELISA in Human;Mouse;Rat.Hundratusentals antikroppar är tillgängliga Rabbit Polyclonal Topoisomerase II alpha/TOP2A Antibody. Validated in WB and tested in Human.
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av H Sonesson · 2017 — verkar bli mindre med anti-pHH3 än vid räkning av mitoser, som är mer Ki67/MIB-1, mitosin, survivin, pHH3 and DNA topoisomerase Iiα in human anaplastic

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Sep 7, 2009 1 More than 90% of patients with SSc are positive for ANA, and anti-DNA topoisomerase I antibody (antietopo. I) and anticentromere antibody are

Order monoclonal and polyclonal Topoisomerase I antibodies for many applications. Selected quality suppliers for anti-Topoisomerase I antibodies. me and cost. Our aim was to assess the performance of the multiple-bead assay, ELISA, and ID testing methods.